Chelsea and Juventus approach Matchday 5 of the Champions League with security of a knockout spot but still with first place in the group up for grabs.
Juventus won the reverse fixture 1-0 and sit three points clear of the Blues, meaning Chelsea will need to win and increase their goal difference to be able to top the group.
Both sides had big wins at the weekend, with Massimiliano Allegri’s Juve earning an impressive 2-0 win away from home against Lazio.
Wojciech Szczesny will remain in goal, but the defence will likely be without Giorgio Chiellini again as he nurses an Achilles injury.
That could leave Leonardo Bonucci, who scored both goals from the penalty spot against Lazio, and Matthijs de Ligt to go again at centre-back, with Juan Cuadrado and Alex Sandro on the right and left of the defence respectively.
Aaron Ramsey will miss in midfield so Manuel Locatelli and Weston McKennie should operate in the middle, with Federico Chiesa moving to the right-hand side and Adrien Rabiot continuing on the left.
Paulo Dybala will face a late fitness test but Juve are hopeful of his availability, and he could be thrust into the side alongside former Chelsea man Alvaro Morata up front.
Thomas Tuchel’s Chelsea side is on fire in all competitions and they could reintroduce some heavy armoury up front.
Defensively, though, Andreas Christensen could come into the line up in place of Trevoh Chalobah, joining Thiago Silva and Antonio Rudiger in the back three in front Edouard Mendy in goal.
Reece James and Ben Chilwell should keep their positions in the wing-back roles either side of Jorginho and Ngolo Kante, with Mateo Kovacic still out injured.
Timo Werner returned to the bench against Leicester and could be in line to start, while Romelu Lukaku has also recommenced training.
This could come just too early for both of them, though, with Mason Mount and Callum Hudson-Odoi once again likely to support Kai Havertz up front.